فهرست نشریات علمی دسترسی آزاد ایران

Introduction: Insomnia is a common sleep disorder that can affect the mood, alertness, memory, security and daily functioning. Currently, the most commonly used drugs in the treatment of insomnia are the benzodiazepines, whose incidence of adverse events, such as cognitive disorders, drug dependence and reversal of symptoms after discontinuation restricts their use. This necessitates the need for more efficient treatments. In Iranian traditional medicine, insomnia and its therapies are widely discussed. In this study, it is revised the effect of materia medica on insomnia in traditional medicine. Method: This study is a library and literature review. The effective drugs in treating insomnia are searched in six reference books on pharmacology of traditional medicine, including The Canon of medicine, Alabnie an haghayegh al Advie, Reyaz al Advie, Tazkare Davood Antaki, Tohfat Al-momenin and Makhzan-al-advie. The study is performed in several stages (finding keywords, searching for resources, and preparation of lists, finding synonyms, classifying, summarizing and rating the results by scores). Results: 28 materia medica were found to the treat insomnia, among which 25 cases had a plant origin and the rest were of animal origin. The results of this study are sorted in a table based on their score of effectiveness. The highest scores found to correspond to Lactuca sativa L., Viola odorata and Cucurbita moschata whose sedative and hypnotic effects have been shown in animal or human studies. Discussion & Conclusion: The obtained results showed that materia medica can help to conduct future clinical trials to obtain new drugs which are effective in insomnia treatment.