Investigating the association between metabolic syndrome components in the first trimester of pregnancy with gestational diabetes occurrence
نویسندگان
1 Master of Reproductive Health, Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
2 Associate Professor, Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
3 Religion and Health Studies Center, Department of Environmental Health, East Tehran Public Health Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 PhD Student of Human Resource Processing, Azad University Branch of Tehran Markaz, Tehran, Iran
5 Midwifery Graduate, Department of Reproductive Health and Midwifery, Faculty of Medical Sciences, Hamedan University, Hamedan, Iran
doi
47797چکیده
Objective: Given the high prevalence of metabolic syndrome and GDM in pregnancy and their impacts on maternal and newborn outcomes, this study was performed to assess the relationship between the components of metabolic syndrome in the first trimester with gestational diabetes occurrence. Materials and Methods: A fasting blood sample was obtained for measuring fasting blood sugar (FBS) triglyceride (TG) and High-Density Lipoprotein (HDL) levels. If the mother had 3 or more of the following criteria, they were considered as having gestational metabolic syndrome (GMS). 1-Pre-pregnancy BMI≥Kg/m2 2- FBS≥100 mg/dl, 3- TG≥150 mg/dl,4-HDL<50 mg/dl,5-BP≥130/85 mm/Hg. Results: Gestational diabetes occurred in 78 participants (15% of mothers). The results showed that metabolic syndrome itself (p-value: 0.022) and high triglyceride and FBS levels (p-values <0.001 both) had significant relationships with the occurrence of gestational diabetes. Logistic regression analysis showed increasing maternal age (OR:1.065, p-value: 0.046) and a history of gestational diabetes in previous pregnancies (OR: 6.562, p-value: 0.010) were significantly related to the occurrence of GD. Conclusion: It was observed in this study that among the components of metabolic syndrome, high levels of blood sugar, and triglycerides in the first trimester of pregnancy were associated with the occurrence of gestational diabetes.
