فهرست نشریات علمی دسترسی آزاد ایران

Introduction: Thyroid cancer can affect the quality of life of patients and no validated study has beenconducted to evaluate the quality of life in patients with thyroid cancer in Iran. The purpose of thisstudy was to evaluate the changes of quality of life in patients with thyroid cancer treated withradioactive iodine.Materials and Methods: According to a prospective longitudinal study, quality of life and mood inthese patients were studied by two questionnaires: Short Form Health Survey (SF36) and HospitalAnxiety and Depression Scale (HADS) provided to the patients by the researcher. The questionnaireswere completed one month before iodine injection, on the day of injection, at the end of the secondweek, and sixth month after radioactive iodine injection. The patients were treated in two groups of100 and 150 μ Curie. After completing the questionnaires, the resulting scores at four different timepoints were evaluated and compared.Results: The mean SF36 scores were lower than one month before iodine intake and after 6 months,the mean scores were lower than one month before iodine intake. The mean HADS scores one monthafter iodine intake were not significantly different from the time of iodine intake, but after two weeks,anxiety and depression were reduced, and the result continued till the sixth months. No difference wasfound in the levels of anxiety and depression between the doses of 100 and 150 μ Curie.Conclusion: The highest level of anxiety and depression and quality of life during the first two weeksof iodine intake reduced with time and iodine intake dose did not affect it.