Studies on the Synthesis of Novel 2,4-ThiazolidinedioneDerivatives with Antidiabetic Activity: Synthesis of 2,4-thiazolidinedione derivatives

نویسندگان

1 Department of Pharmaceutical Chemistry, K. L. E's College of Pharmacy Belgum, India

2 Department of Pharmaceutical Chemistry, Pravara rural College of Pharmacy, Loni, Ahemednager, India.

3 Department of Pharmaceutical Chemistry, Y. B. Chavan College of PharmacyAurangabad, India

4 Department of Pharmaceutical Chemistry, Y. B. Chavan College of PharmacyAurangabad, India

5 Department of Pharmaceutical Chemistry, H S K College of Pharmacy Bagalkot, India

doi
10.22037/ijps.v5.41227
چکیده

A new series of thiazolidinedione derivatives were synthesized. The structures of these compounds were established by means of IR, 1H-NMR and elemental analysis. All of the compounds were screened for antidiabetic activity on albino rats.Most of the compounds showed significant antidiabetic activity when compared with the standard drug glibenclamide.