Fatty Acid Composition and Toxicity of Melia azedarach L. Fruits against Malaria Vector Anopheles stephensi: Composition of Melia azedarach fruits and its effect on Anopheles stephensi
نویسندگان
1 Department of Medical Entomology, School of Public Health and Institute of Health Research, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, P.O.Box: 14155/6451, Iran.
3 Department of Medical Entomology, School of Public Health and Institute of Health Research, Tehran University of Medical Sciences, Tehran, Iran
4 Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, P.O.Box: 14155/6451, Iran.
5 Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, P.O.Box: 14155/6451, Iran.
6 Department of Physiology , Faculty of Medicine , Tehran University of Medical Sciences, Tehran, Iran
7 Department of Chemistry, Medicinal Plant Research Center and Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
doi
10.22037/ijps.v2.39557چکیده
The fruit of Melia azedarach L. (Meliaceae) was extracted with hexane, and its fatty acids methyl ester was analyzed using GC/MS. Thirteen components representing 85.1% of the total extract were identified. The major components identified were methyl palmitate (18.8%), methyl linolenate (16.1%) and methyl linoleate (9.8%). The fruits’ extract had a LC50 of 5.5 ppm against the larvae of Anophles stephensi.
