فهرست نشریات علمی دسترسی آزاد ایران

AbstractBackground and aimVomiting as a side effect of chemotherapy causes to refuse or delay in treatment by most cases. Nowadays,for controlling these side effects researchers attempt to use noninvasive-, safe- and low cost methods, insteadof expensive drugs with various side effects. This study aimed to assess effect of reflexotherapy on vomitingreduction among patients under chemotherapy, in oncology-hematology ward of Zahedan's Ali Ebn AbitalebHospital in 2010.Materials and MethodsThis study was a before and after clinical trial (pre-test and post-test) with a group of 37 patients. Theparticipants were selected using purposeful sampling method and based on the results of a pilot study. Theywere also considered once in the control group (receiving anti-vomiting drug Granisetron) and after 15 to 20days in the interventional group (receiving reflexotherapy in a period of 10 minutes for each leg). TheSummary of Morrow Questionnaire and CTCv2.0  Y/WX FindingsThe mean age of samples was 44.73 ±13.38 (years). Majority of participants were married and women.Patients were in their second to 15th cycle of chemotherapy; receiving Cisplatin–Gemzar or Adriamycincyclophosphamideand were from breast cancer cases. Assessment of severity of vomiting during first 24hours showed more sever vomiting in the first 4 hours among control group than interventional group(p<0.001), but it was more severe in interventional gropup than control group in third 4 hours (p<0.001) andthe second 12 hours (p=0.006). During the second 4 hours, severity of vomiting was not significantlydifferent between the two Groups (p=0.313). Finnally, the results showed no significant difference betweentwo treatment methods respecting their effect on severity (p=0.153) and the number of vomiting (p=0.239)during the 24 hours after treatment.ConclusionAlthough reflexotherapy was not shown to have positive effect on chemotherapy induced vomiting ofpatients but it caused to reduce severity and number of vomiting in the first 4 hours after chemotherapyamong patients with moderate and sever vomiting. Therefore, experimental study using reflexotherapy isrecommended in multiple sessions.Key words:Chemotherapy, Vomiting, Reflexotherapy.REFERENCES-Akbari ME et al (2009). [Iran Cancer Report]. 1st edition. Tehran, Darolfekr Publishing. (Persian).-Azadeh P et al (2006). Granisetron effects on ECG in cancer patients receiving chemotherapy. Pejouhandeh Journal,Shahid Beheshti University of Medical Sciences. 11 (4) 241-244. 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Data was analyzed using central and dispersion indexes as well as Wilcoxon and Mann-Whitney tests and Marginalmodeling (generalized estimating equations GEE).(Common Toxicity Criteria Version 2) of National Cancer Institute of America were used for making a questionnaire to data collection. Face and content validity ofquestionnaire and its reliability (Chronbach alpha Coefficient =