Periodontal therapy as an adjunctive modality for HbA1c reduction in type‑2 diabetic patients
نویسندگان
1 Departments of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University, Riyadh, Saudi Arabia
2 Departments of Diabetes Research
3 Departments of Diabetes Research
4 Department of Dental Public Health, Identiti Dental Centre Departments of 2 Research Support
5 Departments of Dental, Dr. Mohan’s Diabetes Specialities Centre, “WHO Collaborating Centre for Non-communicable Diseases Prevention and Control, and ICMR Centre for Advanced Research on Diabetes”, Chennai, Tamil Nadu, India
doi
چکیده
OBJECTIVES: This study aimed to evaluate the role of nonsurgical periodontal therapy in improvingglycemic control among type 2 diabetes mellitus (T2DM) patients.MATERIALS AND METHODS: Adult T2DM patients with mild‑to‑moderate periodontal disease,reporting to a tertiary care diabetes center in South India, from January to June 2014, were enrolledin the study. Medical management of T2DM along with diet and physical exercise was an inclusioncriterion. Patients with factors affecting periodontal health and an inability to follow‑up were excludedfrom the study. All patients underwent nonsurgical periodontal therapy (scaling, root planing, andirrigation of chlorhexidine [0.12%]). Periodontal status and glycated hemoglobin A1c (HbA1c) wereassessed preoperatively and 6 months posttreatment. Dental status, diabetic history, and demographiccharacteristics were recorded to evaluate confounding roles.RESULTS: A total of 266 T2DM patients (91 females/175 males; mean age47.65 ± 5.93 years/range 25–55 years), fulfilling the inclusion criteria, were enrolled. The meanpre‑ and post‑treatment HbA1c levels were respectively, 8.44 ± 1.87 and 7.98 ± 1.81, with a meanreduction of 0.46 ± 0.26 (P < 0.001). Significant HbA1c reduction (P < 0.001) was observed in patientswith good pretreatment glycemic control (0.54 ± 0.26; 7.9%), regular follow‑up (0.51 ± 0.28; 6.2%),and good oral hygiene (0.60 ± 0.49; 8.0%).CONCLUSION: Nonsurgical periodontal therapy is associated with significant HbA1c reductionamong T2DM patients with mild‑to‑moderate periodontitis after a 6‑month follow‑up period.
