Effect of yoga training on inflammatory cytokines and C‑reactive protein in employees of small‑scale industries

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چکیده

OBJECTIVE: The present study intends to see the effect of yoga practices on lipid profile,interleukin (IL)‑6, tumor necrosis factor (TNF)‑α, and high‑sensitivity‑C‑reactive protein (hs‑CRP)among apparently healthy adults exposed to occupational hazards.MATERIALS AND METHODS: In the present study, 48 participants aged 30–58 years (41.5 ± 5.2)who were exposed to occupational hazards were randomized into two groups, that is, experimentaland wait‑list control. All the participants were assessed for lipid profile, IL‑6, TNF‑α, and hs‑CRP atthe baseline and after completion of 3 months of yoga training intervention. The experimental groupunderwent yoga training intervention for 1 h for 6 days a week for 3 months, whereas control groupcontinued with their daily activities except yoga training. Data analysis was done using statisticalsoftware SPSS Version 20.0. Data were analyzed using paired t‑tests and independent t‑test.RESULTS: The results of within group comparison revealed highly significant changes incholesterol (P < 0.001), high‑density lipoprotein (P < 0.001), low‑density lipoprotein (LDL)(P < 0.01),hs‑CRP (P < 0.01), IL‑6 (P < 0.001), and TNF‑α (P < 0.001) in experimental group. Comparisonbetween experimental and control group revealed significant changes in cholesterol (P < 0.01),LDL (P < 0.05), IL‑6 (P < 0.01), TNF‑α (P < 0.01), and hs‑CRP (P < 0.01).CONCLUSION: A yoga‑based lifestyle intervention seems to be a highly promising alternative therapywhich favorably alters inflammatory markers and metabolic risk factors.