فهرست نشریات علمی دسترسی آزاد ایران

Background: Breast cancer is the most common cause of death in women in the age rangeof 35‑55 years. Each year, one or two cases of breast cancer per 1000 women are diagnosedas new cases. Despite the serious prognosis and high rate of morbidity, mortality, andpathogenicity, in the case of early diagnoses, the prognosis will be better. The aim of thisstudy was to investigate the age trends in breast cancer patients with different sizes of tumorsin Breast Cancer Research Center of Isfahan University of Medical Sciences in 2001‑2010.Materials and Methods: The information in radiotherapy and oncology of Isfahan University ofMedical Sciences and Milad Hospital from 2001 to 2010 were coded and analyzed. Frequencyof patients’ age groups, tumor sizes and the year of cancer diagnosis were calculated.Correlation test was used for data analysis in statistical analysis in social science (SPSS)software version 18. Findings: Among the 3722 patients with breast cancer, the highestrelative frequency distribution, respectively was observed in the age of 40‑49 years (34.4%),50‑59 years (26.6%), 30‑39 years (17.7%), 60‑69 years (13.2%), 20‑29 years (2.5%), 70 yearsand older (5.2%) and less than 20 years. Relative frequency distribution of tumor sizes in avariety of 5 cm (T2) was with the frequency of 59.8%, and then 26% at 5 cm (T3), 10.5% at2 cm (T1), 3.1% at T4 and 0.6 at In‑situ, respectively. Conclusion: The investigation of agetrends showed that diagnosis rate of breast cancer increased from 2001 to 2004. It reached itshighest value in 2006 at the age range of 30‑39 years. Then, the trend has been downward, andit has continued to decline until 2010, whichcould be the result of the equipping screeningsystem and recording the malignant cases.85.8% of the examined tumors in T2 and T3group were visible and may be disturbing.Comparing the frequency distribution of theinfected population showed that the highestincidence of breast cancer diagnosis were inthe age range of 40‑49 years. It seems that aslong as the mass has not reached an obviouspalpable state, it has not been diagnosed.