فهرست نشریات علمی دسترسی آزاد ایران

Background: Infection control is an essential part of caring for hospitalized infants. Withregard to the change of bacterial resistance over time and places, as well as the need forperiodic studies on the effectiveness of antiseptics, this study aims to compare the effects ofboth solutions of povidone-iodine and chlorhexidine on skin bacterial flora among hospitalizedinfants. Materials and Methods: This clinical trial recruited 98 hospitalized infants and each ofthe above-mentioned solutions has been applied to a small area in the left or right side of theinfants’ bodies. Skin cultures were taken before, immediately after and 2 h after the randomlychosen infants’ skin areas that were disinfected by each solution (588 skin cultures in total).Colony count and determination of microorganism types were done by only one person in asingle laboratory. The study has been conducted in two teaching hospitals in Isfahan, Iran.Results: Staphylococcus epidermidis was the most common microorganism prior to skindisinfection by either solution. Two hours after disinfection, “Staphylococcus epidermidis” and“Staphylococcus epidermidis and kelebsila” had the highest frequencies of 3.1% and 3.1%,respectively. Before and 2 h after disinfection, distribution of different types of microorganismshad no significant difference between the two groups (P = 0.84 and 0.13, respectively); however,the difference was significant immediately after disinfection, P < 0.01. Conclusion: The presentstudy demonstrated that 10% povidone-iodine solution has more significant effect on reductionof skin pathogens promptly after application compared to 2% chlorhexidine. Therefore, priorto any catheterization procedures, it is imperative to use 10% povidone-iodine solutions forskin disinfection.