Can use the NMP22 BladderChek Decrease the Frequency of Cystoscopy in the Follow up of Patients with Bladder Carcinoma ?

نویسندگان
doi
چکیده

Methods: 38 patients known to have bladder cancer, undergoing surveillance, were subjected to abdominal- pelvic ultrasonography, NMP22 BladderChek test; urine cytology followed by check cystoscopy and biopsy if indicated. The accuracy of these tools was compared by their sensitivity and specificity as well as diagnostic likelihood ratio in detecting recurrence of bladder cancer. Results: The sensitivity and positive likelihood ratio of NMP22 BladderChek were superior to urine cytology (95% and 8.5 vs 50% and 4.5, respectively), while both diagnostic modalities were equal in terms of specificity (88.9%). Conclusions: NMP22 BladderChek is a simple in-office test which proved in the current study to be highly sensitive in detecting recurrence, it can change the classical regimen for follow up of bladder cancer cases; reducing the number of check cystoscopies  for these patients.