فهرست نشریات علمی دسترسی آزاد ایران

Methods: Two hundred and forty one  essential hypertensive patients, were included in a cross-section study for the presence of albuminuria and its relation to estimated glomerular filtration rate (eGFR); their history of hypertension ranges from 12-240 months with a mean of 75±54 (aged 48±11 years, range 20 - 76 years) any patient with doubtful history of essential hypertension were excluded from the study, patients included in the study  were 148 (61%) males and 93 females, their mean  body mass index was 27±5 kg/m 2 . Results: Prevalence of normoalbuminuria was 59%, microalbuminuria 31%, and macroalbuminuria 10%. eGFR was significantly decreased in microalbuminuria and macroalbuminuria groups, on further analysis this reduction in eGFR was not related to severity of hypertension but to its duration. There was a significant increase in the duration of history hypertension in eGFR < 60 ml/min/1.73 m 2 in comparison to eGFR > 60 ml/min/1.73 m 2 in all groups (Normo, Micro and Macroalbumiuria). There was no significant difference eGFR between controlled and uncontrolled groups (either by MDRD or Mayo clinic formula). Conclusion: Albuminuria is a risk marker for prediction of the progression of nephropathy in Egyptian essential hypertensive patients and may reflect hypertensive injury to the kidney.