فهرست نشریات علمی دسترسی آزاد ایران

Methods: : In the present study we investigated the prevalence of H. pylori infection in 87 HD patients by three methods: serum anti-H. pylori IgG, H. pylori stool antigen (HpSAg) and Urease Breath Test (UBT). All the three methods confirmed each other and when 2 out of the 3 methods showed positive findings, patients were regarded as H. pylori -positive. We also assessed the relationship between clinical factors, serum urea nitrogen, creatinine levels, and duration of dialysis, age and gender with the prevalence H. pylori in these patients. Results: : Eighty seven HD patients (48 male and 39 female) with the mean age of 54.4±16.7 years old and mean dialysis duration of 36.2±33.5 months were assessed. Fifty five (63.2%) of them had dyspepsia. The prevalence of H. pylori infection was 44.8%. Multivariate logistic regression analysis revealed the serum urea nitrogen level was significantly associated with H. pylori prevalence (P=0.03, 95% CI: 1.4-35.8). High serum urea nitrogen seems to correlate with a high prevalence of H. pylori infection. The prevalence of H. pylori infection was low in young patients, but high in elderly patients (P=0.04, 95%CI: 0.97-10.3). There was no significant correlation between gender, duration of dialysis, serum Cholesterol, Triglyceride, creatinine, Hemoglobin, albumin, calcium and phosphor and H. pylori infection in these patients. Conclusions: : Among dialysis patients, the proportion of H. pylori-positive patients was not low. Dialysis treatment may influence H. pylori infection.