فهرست نشریات علمی دسترسی آزاد ایران

Background: : Peritoneal dialysis (PD) and Hemodialysis (HD) have been considered as two standard treatment methods in patients with end stage renal disease. It has been proposed that PD patients have a more protected volume status leading to a better renal transplantation outcome and lower incidence of post-transplant (DGF) delayed graft function , while HD exacerbates the immune disturbance by recurrent activation of inflammatory response, oxidative stress and free radical production that can contribute to DGF. Objectives: In this retrospective study, we analyzed the effect of peritoneal dialysis (PD) or Hemodialysis (HD) on patients’ survival, graft survival, delayed graft function (DGF), acute rejection and early and late complication after living-donor renal transplantation. Results: Of 143 patients who had their first living kidney transplant in, 69 patients (M/F 48/21 mean age: 35.3 ± 15.9 years) were in PD group and 74 patients (M/F 38/36 mean age: 40.7 ± 13.3 years) were in HD group. Mean age of donor in PD and HD group were 28.4 ± 4.4 and 29.7 ± 5.6 years. The number of diabetic patient in PD and HD groups were 11/69 (13.6%) and 16/74 (16.2%) (P: 0.4). The rate of delayed graft function, early acute rejection in PD and HD groups was as the followings: 3/69(4.3%) versus 3/74(4.1%) and 3/69(4.3%) versus 2/74 (2.7%). Comparison of overall five years patient and graft survival between the PD and HD patients showed no significant difference by log-rank test ( P = 0.13 for patients survival), ( P = 0.26 for grafts survival). Conclusions: We found that the choice of dialysis modality does not influence the overall patient and graft survival and the rate of specific complications in living-donor renal transplantation.