Comparison of Serum and Urine Neutrophil Gelatinase-Associated Lipocalin (NGAL) With Serum Creatinine in Prediction of Kidney Suitability for Transplantation

نویسندگان
doi
10.5812/numonthly.5002
چکیده

Background: When using brain dead donors for organ donation, assessment of kidney function before the procedure is essential. Objectives: It would be ideal to find an early marker of viability of donor kidneys that is more accurate than creatinine. Results: There were 31 males and 21 females with the mean age of 29.7 ± 14.3 (6-58) years. Thirty one patients became brain dead due to car accidents. The mean time of admission time before harvest was 12.6 ± 5.8 (3-30) hours. We did not discover any correlation of serum creatinine with serum or urinary NGAL at any time before the organ harvesting. However, serum NGAL level measurement 2 hours after admission correlated significantly with other hours\' measurements (4, 6, 8 hours, r > 0.9; P < 0.001). Conclusions: The serum NGAL level, especially at 2 hours after admission to the ICU, should be evaluated with kidney function after transplantation to get the accurate predictive value.

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