Comparison of Vitamin E and L-Carnitine, Separately or in Combination in Patients With Intradialytic Complications

نویسندگان
doi
10.5812/numonthly.10670
چکیده

Background: The most common complications during dialysis are hypotension and muscle cramps. There are many strategies to prevent and treat these complications. Objectives: The aim of this study is to evaluate effects of vitamin E and L-carnitine supplementation alone and in combination on intradialytic complications. Results: All three treatments significantly reduced frequency of muscle cramps in comparison to baseline values. Vitamin E alone and in combination with L-carnitine reduced the frequency of muscle cramps more effectively. Hypotension was significantly lower in combination therapy in comparison to baseline values and vitamin E treatment. Conclusions: Vitamin E and L-carnitine both have comparative effects on intradialytic complications. As the combination use of vitamin E and L-carnitine could more effectively reduce the intradialytic complications, it is recommended for daily use in hemodialysis patients.