فهرست نشریات علمی دسترسی آزاد ایران

Background: Protein-bound toxins such as indoxyl sulfate (IS) are not efficiently removed by conventional hemodialysis (HD). Objectives: To improve the removal of IS, we performed an in vitro study to evaluate the effects of high dissolved hydrogen on the dissociation of IS from albumin using simulated HD. Results: IS was significantly dissociated from albumin using dialysate with high dissolved hydrogen compared with conventional dialysate (P < 0.05). Conclusions: Effective removal of IS is expected using a dialysate with high dissolved hydrogen.