فهرست نشریات علمی دسترسی آزاد ایران

Background: Male idiopathic infertility is characterized by abnormal semen parameters, including sperm concentration, motility, and morphology. Various hormonal and experimental therapies are employed to address this condition. Objectives: This study investigates the effect of sesame on sperm concentration, morphology, and motility in infertile men compared to combination drug therapy. Results: Post-intervention, sperm motility was 42.6 ± 9.23% in the sesame group vs. 44.02 ± 6.61% in the combination drug group (P = 0.43), concentration was 33.82 ± 10.8 million/mL vs. 46.57 ± 9.62 million/mL (P < 0.001), and morphology was 27.22 ± 10.23% vs. 28 ± 7.59% (P = 0.58). Within-group analysis showed significant improvements in all parameters for both groups (P < 0.001). Conclusions: Both sesame and combination drug therapy improved sperm parameters, with combination drugs showing greater efficacy in enhancing sperm count and motility, while sesame significantly improved morphology.