فهرست نشریات علمی دسترسی آزاد ایران

Objective : Long non-coding RNAs (lncRNAs) are characterized as non-coding transcripts greater than 200 nucleotides. lncRNAs have extensive molecular connections with proteins and microRNAs, which are important in the regulation of gene expression in physiologic and pathologic states including cancer. About 18% of human LncRNAs were recently found to be associated with tumours. Many studies indicated that aberrant expression of LncRNAs play key roles in the progression and metastasis of NSCLC. In this study we evaluated the expression of long non-coding RNAs: GHET1, BACE1-AS, PANDA, UCA1 in non-small cell lung cancer.