فهرست نشریات علمی دسترسی آزاد ایران

Introduction: Zinc deficiency may aggravate the effect of oxidative stress on RBC (Red Blood Cell) of chronic uremia. In this study, there is an attempt to show the relationship between the plasma zinc level and RBC osmotic fragility in hemodialysis patients. Results: The mean serum zinc concentration among the participants increased and it was statistically significant (p<0.05). Erythrocytes at day 0 (59+/_ 3.5) were significantly (P < 0.05) more fragile in hypotonie saline than those at day 43(38+/_ 2.9), (at NaCl 40%). No significant changes were noted in the level of Hb Discussion: In this trial, oral zinc supplementation caused a significant rises in the plasma zinc level after 6 weeks. Although Hb concentration was not changed during the trial the level of osmotic fragility in red cells reduced significantly.