فهرست نشریات علمی دسترسی آزاد ایران

Objective: There is a substantial amount of evidence suggesting that alteration in some hormones is associated with depression. The aim of the study was to assess the serum level of thyroid hormones and leptin in patients with depression. Results: Leptin and T3 levels were significantly decreased and T4 rose in the depressed women as compared to the healthy controls (P < 0.05, P < 0.001, and P < 0.001 respectively). Furthermore, the serum level of leptin was significantly lower and T4 was significantly higher in sever depressed women compared to moderately or mildly depressed women (P < 0.001 and P < 0.01, respectively). Conclusions: This study showed that thyroid and leptin hormones malfunction in depressed women. Thus, inclusion of thyroid and leptin screening test in the case of deessed patients might be required in proper management schedules.