فهرست نشریات علمی دسترسی آزاد ایران

Background: Neonatal jaundice is the most common cause of hospitalization in the first month of life. Factors that reportedly affect the severity of neonatal jaundice include: maternal, prenatal and neonatal factors as well as environmental factors (such as zinc). Animal study demonstrated a decrease in serum bilirubin level after zinc treatment in hyperbilirubinemic rats. Objectives: The current study aimed to investigate serum zinc level in the neonates with idiopatic jaundice. Results: The mean value of the zinc serum level was 1024.74 ± 245.17 μmol/L in the control group and 841.42 ± 211.99 μmol/L in the case group (P < 0.001). There was no significant correlation between zinc level and factors such as maternal age, multi parity, mode of delivery, hospitalization and gender of infants (P > 0.05). Also, no significant correlation was observed between serum levels of Na, blood urea nitrogen (BUN), creatinine (Cr), white blood cell (WBC), platelet, hematocrit (Hct) and zinc (P > 0.05). Conclusions: The level of serum zinc in the neonates with hyperbilirubinemia jaundice was lower than that of the ones without jaundice. It seems that zinc has a protective effect. However, more studies are needed for better decision making.