فهرست نشریات علمی دسترسی آزاد ایران

Introduction: Severe hypersensitivity reactions to sodium thiopental are rare but documented adverse events. During the COVID-19 pandemic, shortages of standard sedative agents prompted the increased use of thiopental as an alternative sedative for intubation in critically ill patients. However, data on the safety of sodium thiopental in COVID-19 patients receiving antiviral therapy, including remdesivir, remain limited. Conclusions: This case highlights the risk of suspected anaphylaxis after sodium thiopental administration in critically ill patients with COVID-19. Clinicians should exercise caution when selecting sedative agents for intubation in this population, taking into account potential drug interactions and hypersensitivity risk. Further investigation is required.