فهرست نشریات علمی دسترسی آزاد ایران

Vancomycin is an essential glycopeptide antibiotic facing challenges from resistant bacterial strains such as vancomycin-intermediate Staphylococcus aureus (VISA) and heterogeneous VISA (hVISA). Timely and precise identification of these strains is vital for efficient infection control. This report explores using aptamer-based biosensors as a novel solution for the rapid detection of hVISA. Aptamers, short, single-stranded nucleic acids, exhibit remarkable specificity and strong affinity for their targets, making them outstanding candidates for biosensor creation. These biosensors offer affordability, ease of customization, and swift performance, making them highly appropriate for medical settings. By utilizing electrochemical detection techniques, aptamer-based biosensors facilitate real-time tracking of vancomycin concentrations and may also contribute to the efficient detection of hVISA, addressing urgent demands in infectious disease control.