فهرست نشریات علمی دسترسی آزاد ایران

Background: Magnetic resonance imaging (MRI) plays a critical role in diagnosis of multiple sclerosis (MS) and detecting brain changes during the course of the disease, but many aspects of MR Imaging such as its relationship with MS disabilities has remained unrecognized yet. One of the MS disabilities is cognitive impairment (CI), with an incidence of about 45% to 60%. Objectives: The purpose of this study was to examine the relationship between cognitive function and the volume of the brain lesions by assessing some of the sub-items of cognition. Results: There were no significant correlation between total lesion volumes and MoCA score. But significant correlations between total lesion volumes with visuospatial/executive function were found in persons with higher education. Conclusions: White matter lesion volumes have influence on some of the cognition sub-items in MS patients. Furthermore, MRI determinants can be useful for clinicians to evaluate cognition in MS patients.