فهرست نشریات علمی دسترسی آزاد ایران

Background: Triolein emulsion infusion into the brain produces transiently increased vascular permeability. Objectives: The purpose of this study was to find the minimum percentage of triolein emulsion required for studying vascular permeability with minimal brain edema. Results: The lesion hemispheres showed mild hyperintensity due to edema on T2-weighted images, and contrast enhancement on post-contrast T1-weighted images in cats of group 1-5. CERs showed statistically significant differences between the control group and group 3 (P = 0.006), group 4 (P = 0.003), and group 5 (P < 0.001). However, SIRs were significantly different between the control group and group 5 only (P < 0.001). Conclusion: The minimum concentration of triolein emulsion required to increase vascular permeability adequately with minimal brain edema in a cat model was 0.5%.