فهرست نشریات علمی دسترسی آزاد ایران

Background: Malfunctions of totally implantable central venous ports (TICVPs) have become a problem, as the usage of TICVPs has increased enormously. Objectives: This study evaluated factors related with catheter malfunctions of TICVPs. Results: In the retrospective study, the 32 malfunctioning TICVPs were caused by fibrin sheath formations (n = 15), chamber thrombosis (n = 8), TICVP rotation (n = 5), catheter migration (n = 2), and blood clots within the catheters (n = 2). Multivariate analysis showed that being female was a significant factor for poor patency rates of TICVPs (hazard ratio: 5.06; 95% confidence interval (CI) 1.32 - 19.46, P = 0.018). In the prospective study, two chamber thromboses occurred in Celsite® (n = 1) and Humanport® (n = 1). The primary patency rates of both Celsite® and Humanport® were 98.9% at 6 months, respectively. Conclusion: Our data suggest that catheter malfunctions of TICVPs are more common in females than males. The incidence of TICVP malfunctions does not differ between the two devices (Celsite® vs. Humanport®).