فهرست نشریات علمی دسترسی آزاد ایران

Background: The tendency of myxofibrosarcoma (MFS) to have a non-nodular appearance on magnetic resonance imaging (MRI) may present a challenge in detection of local recurrence. Appropriate index of suspicion of expected imaging appearance can alleviate this challenge. Objectives: Our objectives were to determine if: 1) imaging pattern at recurrence is associated with delayed diagnosis, and 2) appearance at recurrence can be predicted based on appearance at presentation. Results: There was substantial agreement among the 3 readers (k = 0.72, 95% confidence interval: 0.59 - 0.85). Half of all infiltrative cases were associated with a delay in diagnosis, compared to 10% of mixed or focal cases; however, there was no statistically significant association between infiltrative pattern at recurrence and delayed diagnosis (P = 0.08). In 70% of cases, recurrence had the same appearance as presentation, suggesting a trend; however, there was no association between appearance at baseline and recurrence (P = 0.1). Conclusion: Imaging appearance at baseline does not reliably predict imaging appearance at recurrence. Therefore, a high index of suspicion for the infiltrative pattern is required in assessment of post-operative MRIs in patients with MFS.