فهرست نشریات علمی دسترسی آزاد ایران

Objectives: To explore the value of T 2 and T 1 mapping in the early detection of degenerating articular cartilage. Results: In group A, immunohistochemistry found that collagen type II decreased in the treated knees. T 2 and T 1 values were higher in the treated knees than the controls (P < 0.001). In group B, Alcian blue staining showed reduced proteoglycan in the treated knees. The T 1 values in the treated knees were higher than the controls (P < 0.001). Conclusion: T 2 and T 1 mapping may be useful in the early diagnosis of cartilage degeneration. The changes in collagen content of the cartilage were related to T 2 relaxation time; whereas, T 1 relaxation time was affected by both collagen and proteoglycan.