فهرست نشریات علمی دسترسی آزاد ایران

Background: In order to reduce the occurrence of bone cement leakage, bone filling mesh container technique can be a prior choice for the treatment of vertebral metastases with damaged posterior margin of the thoracolumbar vertebral body. Objectives: The purpose of this retrospective study was to compare the efficacy and safety of percutaneous balloon kyphoplasty (PKP) and bone filling mesh containers (BFMCS) in the treatment of vertebral metastases with posterior vertebral body damage. Results: All patients underwent successful operation. The operation time of the PKP group was 42.65 ± 7.84 minutes, and 42.95±8.48 minutes in the BFMCS group (P = 0.91). Both groups differed significantly when the results were compared with those measured before treatment. VAS dropped from 7.50 ± 0.95 points before operation to 1.20 ± 0.41 points at 6 months follow up in PKP group (P < 0.001), in the BFMCS group VAS dropped from 7.50 ± 0.94 points before operation to 1.45 ± 0.51 points at 6 months after operation (P < 0.001). The ODI of the PKP group dropped from 75.80±4.76 before operation to 12.05 ± 1.47, 6 months after operation (P < 0.001), ODI dropped from 75.00 ± 4.34 before operation to 11.60 ± 1.39 at 6 months follow up in the BFMCS group (P < 0.001). In the PKP group, 15 vertebral bodies (40.5%, 15/37) occurred bone cement leakage, but the patients had no clinical symptoms of bone cement leakage. Cement leakage occurred in one case in the BFMCS group. There were no complications such as pulmonary embolism, paraplegia or perioperative death. Conclusion: The application of bone-filling mesh container for treating patients with thoracolumbar osseointegrated metastases could significantly reduce the leakage rate of bone cement, and is similar to traditional PKP in pain relief and activity improvement.