فهرست نشریات علمی دسترسی آزاد ایران

Background: Osteoporosis is a common chronic disease that can cause fractures and other complications. Early diagnosis and prompt treatment of this disease can reduce the risk of fracture. The trabecular bone score (TBS) is a valuable tool for evaluating bone microarchitecture in patients with osteoporosis. Objectives: The present study aimed to evaluate the association of TBS score with bone mineral density (BMD) as the gold standard in patients with osteoporosis. Results: In this study, the majority of the patients were female (88.2%) and younger than 65 years (63.0%). Osteopenia and osteoporosis were diagnosed in 42.1% and 18.9% of the patients, respectively. The sensitivity of TBS for diagnosing osteoporosis versus osteopenia and osteopenia versus a normal status was higher in patients aged ≥ 65 years compared to those aged < 65 years (63.33% vs. 27.78% and 86.66% vs. 63.63%, respectively). Overall, TBS demonstrated a high diagnostic ability for differentiating osteoporosis versus normal BMD (AUC = 0.911, P < 0.001). Conclusion: Based on the findings, TBS alone is not sufficient for diagnosing osteoporosis and cannot replace BMD. Therefore, a combination of BMD and TBS techniques can be the best approach for diagnosing osteoporosis, especially in patients aged ≥ 65 years.