فهرست نشریات علمی دسترسی آزاد ایران

Background: The effect of microwave ablation on small hepatocellular carcinoma is not significantly different from that of surgical resection. Accurate assessment of the ablation effect is crucial for ensuring the safety and effectiveness of hyperthermia. Objectives: This study aimed to explore the feasibility and accuracy of supersonic shear wave elastography (SWE) in quantitatively evaluating the microwave ablation margin of the liver. Results: A total of 144 effective ablations and 131 effective pathological results were obtained. Within the same ablation time, the elastic modulus increased in the surrounding normal tissue, ablation margin, and ablation center regions in a stepwise manner (P < 0.01). However, in the ablation center region, the elastic modulus decreased in a stepwise manner with the shortening of ablation time [60 s (97.16 ± 14.58 kPa) > 30 s (77.84 ± 9.64 kPa) > 15 s (38.92 ± 3.12 kPa)], with statistically significant differences (F = 2,131.832, P < 0.01). The elastic modulus of the ablation margin region at different ablation times remained between 22.68 - 23.56 kPa. Conclusion: The elastic modulus range in the ablation margin region after microwave ablation is relatively fixed. Shear wave elastography aids in the quantitative evaluation of the ablation margin region of the liver and has high practical value in monitoring and evaluating ultrasound ablation.