فهرست نشریات علمی دسترسی آزاد ایران

Background: In a severe oxidative stress condition, balance of oxidant-anioxdiant system of the body breaks down, which is in order to produce more oxidants and, after that, important macromolecules such as DNA undergo irreversible changes. There are reports indicating the therapeutic effects of the date. This study was aimed to evaluate the effect of date kernel`s on antioxidant capacity and the rate of glutathione peroxidase activity in the Rat`s blood serums and erythrocytes after intraperitoneal administration. Results: Rates of antioxidant capacity of serum and erythrocyte in the concentration of 25, 50, and 100 were 23.40, 40.40, 54.34 and 124.35, 156.73, 198.29, respectively, and rates of glutathione peroxidase activity of serum and erythrocytes in the concentrations above were 0.87, 0.232, 0.306 and 0.116, 0.285, 0.653, respectively. Conclusion: Rats which were injected by a more concentration of date kernel`s extract had more total antioxidant capacity and the rate of their glutathione peroxidase activity was more than the others indicating an appropriate effectiveness of the date kernel`s extract.