Role of Fresh Frozen Plasma Transfusion in Prevention of Brain Contusion Enlargement in Patients Following Head Trauma

نویسندگان
doi
چکیده

Background: Hemorrhagic progression of a contusion (HPC) is one of the main problems in neurosurgery, which is associated with several adverse effects and increasing the risk of mortality. The present study investigated the effect of transfusion of fresh frozen plasma (FFP) in the prevention of HPC. Results: Contusion level was significantly increased in both groups, but there was no significant difference between the two groups (P>0.05). GCS also improved in both groups after one month, but no significant difference was found between the two groups. The duration of stay in the ICU (132.5 days vs. 9.82.4 days) and hospital (18.12.6 days vs. 13.53.3 days) was significantly higher in the control group (P<0.0001). Mortality (6% in the FFP group and 10% in control group) and complication rates were similar in both groups (P>0.05). Background: Hemorrhagic progression of a contusion (HPC) is one of the main problems in neurosurgery, which is associated with several adverse effects and increasing the risk of mortality. The present study investigated the effect of transfusion of fresh frozen plasma (FFP) in the prevention of HPC. Results: Contusion level was significantly increased in both groups, but there was no significant difference between the two groups (P>0.05). GCS also improved in both groups after one month, but no significant difference was found between the two groups. The duration of stay in the ICU (132.5 days vs. 9.82.4 days) and hospital (18.12.6 days vs. 13.53.3 days) was significantly higher in the control group (P<0.0001). Mortality (6% in the FFP group and 10% in control group) and complication rates were similar in both groups (P>0.05).

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