فهرست نشریات علمی دسترسی آزاد ایران

Introduction: Primary malignant melanoma of the oral cavity is a rare occurrence. This tumor, compared to other malignant tumors of the oral cavity, has higher tendency to metastasize or locally invade the adjacent structures. Its most common site of occurrence in the oral cavity is the palate followed by the maxillary gingiva. Oral melanoma does not have a pathognomonic clinical manifestation and in rare cases, it may not even cause clinical discoloration of the mucosa either; in this case, it is referred to as amelanotic melanoma. Most cases of amelanotic melanomas are metastatic rather than primary tumors. The Survival rate of patients with mucosal melanoma is lower than that of patients with cutaneous melanoma. Prognosis is much poorer for amelanotic melanoma due to difficult and delayed diagnosis compared to cutaneous melanoma.