فهرست نشریات علمی دسترسی آزاد ایران

Introduction: Dystrophic Epidermolysis Bullosa (DEB) poses major challenges, especially for anesthetic management. The main challenge faced is a pediatric patient with a difficult airway requiring general anesthesia. Any airway manipulation leads to immediate and significant trauma with bullae formation, thereby necessitating the need for postoperative ventilation and prolonged hospital stay. It is advisable to avoid any airway interventions, if possible. Conclusions: To date, there is no reported case of DEB being successfully managed with only two drugs, dexmedetomidine infusion and a single dose of ketamine for maintaining spontaneous ventilation (opioid-free anesthesia/OFA) with no airway intervention/manipulation, especially in non-operating room anesthesia (NORA) setting.